| ezetimibe versus placebo (on top statins) | |||
| Enhance, 2008 | ezetimibe 10mg + simvastatin daily versus simvastatin 80mg daily | patients with familial hypercholesterolemia | double blind Follow-up duration: 24 months |
| pactimibe versus placebo | |||
| CAPTIVATE, 2009 NCT00151788 | pactimibe 100mg daily versus placebo | patients with familial hypercholesterolemia and carotid atherosclerosis | double blind Follow-up duration: 15 months (mean) United States, Canada, Europe, South Africa, Israel |
| torcetrapib versus placebo | |||
| RADIANCE 1, 2007 NCT00136981 | atorvastatin combined with 60 mg of torcetrapib versus atorvastatin monotherapy | patients with heterozygous familial hypercholesterolemia | open Follow-up duration: 24 months |
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