See also:
All hypertension clinical trials
All clinical trials of strategy
All clinical trials of more intensive blood pressure lowering strategie
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Treatments
Studied treatment |
low target blood pressure (mean arterial pressure < 92 mm Hg)
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Control treatment |
usual target blood pressure (mean arterial pressure < 107 mm Hg)
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Patients
Patients |
patients with predominantly nondiabetic kidney disease and a glomerular filtration rate of 13 to 55 mL/min per 1.73 m2 |
Baseline characteristics |
Number of antihypertensive drugs |
1.91/1.5 |
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Method and design
Randomized effectives |
840 |
Blinding |
open |
Follow-up duration |
2.2 y |
Number of centre |
15 |
Results
No results available for this trial
- no clinical endpoint reported
Meta-analysis of all similar trials:
strategy in hypertension for non diabetic patients
strategy in hypertension for all type of patients
Reference(s)
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Klahr S, Levey AS, Beck GJ, Caggiula AW, Hunsicker L, Kusek JW, Striker G.
The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group..
N Engl J Med 1994;330:877-84
Pubmed
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Hubmed
| Fulltext
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Lazarus JM, Bourgoignie JJ, Buckalew VM, Greene T, Levey AS, Milas NC, Paranandi L, Peterson JC, Porush JG, Rauch S, Soucie JM, Stollar C.
Achievement and safety of a low blood pressure goal in chronic renal disease. The Modification of Diet in Renal Disease Study Group..
Hypertension 1997;29:641-50
Pubmed
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Hubmed
| Fulltext
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Peterson JC, Adler S, Burkart JM, Greene T, Hebert LA, Hunsicker LG, King AJ, Klahr S, Massry SG, Seifter JL.
Blood pressure control, proteinuria, and the progression of renal disease. The Modification of Diet in Renal Disease Study..
Ann Intern Med 1995;123:754-62
Pubmed
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Hubmed
| Fulltext
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Sarnak MJ, Greene T, Wang X, Beck G, Kusek JW, Collins AJ, Levey AS.
The effect of a lower target blood pressure on the progression of kidney disease: long-term follow-up of the modification of diet in renal disease study..
Ann Intern Med 2005;142:342-51
Pubmed
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Hubmed
| Fulltext
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