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See also:
All acute myocardial infarction clinical trials
All clinical trials of PCI
All clinical trials of thrombolysis + angioplasty
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Treatments
Studied treatment |
immediate transfer for PCI after half-dose reteplase, abciximab, heparin, and aspirin
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Control treatment |
half-dose reteplase, abciximab, heparin, and aspirin, transfer for PCI only if they had persistent ST elevation at 90 minutes (rescue PCI)
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Concomittant treatment |
half-dose lytic therapy (reteplase), aspirin, heparin, and abciximab bolus plus infusion |
Patients
Patients |
STEMI patients under 75 years old within 12 hours of symptom onset who had been admitted to hospitals without PCI facilities |
Method and design
Randomized effectives |
NA / NA (studied vs. control) |
Blinding |
open |
Follow-up duration |
30 days |
Geographic area |
France, Italy, and Poland |
Primary endpoint |
death, reinfarction, or refractory ischaemia at 30 days |
Results
No results available for this trial
- no clinical endpoint reported
Meta-analysis of all similar trials:
myocardial revascularization in acute myocardial infarction for all type of patients
PCI in acute myocardial infarction for all type of patients
Reference(s)
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Di Mario C, Dudek D, Piscione F, Mielecki W, Savonitto S, Murena E, Dimopoulos K, Manari A, Gaspardone A, Ochala A, Zmudka K, Bolognese L, Steg PG, Flather M.
Immediate angioplasty versus standard therapy with rescue angioplasty after thrombolysis in the Combined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial..
Lancet 2008;371:559-68
Pubmed
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Hubmed
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Di Mario C, Bolognese L, Maillard L, Dudek D, Gambarati G, Manari A, Guiducci V, Patrizi G, Rusconi LC, Piovaccari G, Hibon AR, Belpomme V, Indolfi C, Olivari Z, Steffenino G, Zmudka K, Airoldi F, Panzarasa R, Flather M, Steg PG.
Combined Abciximab REteplase Stent Study in acute myocardial infarction (CARESS in AMI)..
Am Heart J 2004;148:378-85
Pubmed
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Hubmed
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