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See also:

  • All acute myocardial infarction clinical trials
  • All clinical trials of PCI
  • All clinical trials of primary PCI
    		•  

    senior PAMI study, 2005

    [NCT00136929] Facebook    pdf : primary PCI - myocardial revascularization for acute myocardial infarction

    Treatments

    Studied treatment primary percutaneous coronary intervention
    Control treatment intravenous thrombolytic therapy

    Patients

    Patients elderly (age >= 70 years) patients with acute myocardial infarction
    Exclusion criteria systolic blood pressure >180 mm Hg; diastolic blood pressure >100 mm Hg; warfarin

    Method and design

    Randomized effectives 252 / 229 (studied vs. control)
    Design Parallel groups
    Blinding Open
    Follow-up duration 30 days
    Primary endpoint death or disabling stroke


    Results

    Endpoint Studied treat.
    n/N     Control treat.
    n/N     Graph RR [95% CI]

    stroke (fatal and non fatal)

    2 / 252
         5 / 229
         0,36 [0,07;1,86]

    In-hospital death

    25 / 252
         30 / 229
         0,76 [0,46;1,25]     0 2 1.0

    Relative risks
    Endpoint Events (%) Relative Risk 95% CI Endpoint definition
    in the trial    		 Ref
    Studied treat. Control treat.
    In-hospital death 25 / 252 (9,9%) 30 / 229 (13,1%) 0,76 [0,46;1,25] at 30 days   
    stroke (fatal and non fatal) 2 / 252 (0,8%) 5 / 229 (2,2%) 0,36 [0,07;1,86] disabling at 30 days   
    The primary endpoint (if exists) appears in blod characters
    Reference(s) used for data extraction:

    Endpoint studied treat. control treat. mean diff

    Absolute risk reduction
    Endpoint Events rate Absolute risk
    reduction (ARR)
    Studied treat. Control treat.
    In-hospital death 9,92% 13,10% -31,8‰
    stroke (fatal and non fatal) 7,94‰ 2,18% -13,9‰

    Meta-analysis of all similar trials:

    myocardial revascularization in acute myocardial infarction for Elderly patients

    myocardial revascularization in acute myocardial infarction for all type of patients

    PCI in acute myocardial infarction for all type of patients

    PCI in acute myocardial infarction for Elderly patients



    Reference(s)

    Trials register # NCT00136929

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